Treatment outcomes in poor metabolizers of cytochrome P450 2A6 with concurrent chemoradiotherapy in locally advanced head- and neck-squamous cell carcinoma

INTRODUCTION: Human Cytochrome 2A6 (CYP2A6) is involved in the oxidative metabolism of the nicotine to the inactive cotinine. CYP2A6 is a primary enzyme in nicotine metabolism, the enzyme has been proposed as a novel target for smoking cessation. MATERIALS AND METHODS: A total of 70 male patients of...

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Detalles Bibliográficos
Autores principales: Aggarwal, Deepa, Singh, Sudhir, Ali, Mohammad, Singh, Abhay, Srivastava, Kirti, Gupta, Rajeev, Bhatt, Madan Lal Brahma, Devi, Seema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851368/
https://www.ncbi.nlm.nih.gov/pubmed/36683922
http://dx.doi.org/10.4103/njms.NJMS_312_21

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