Circulating Biomarkers in Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy is the most common genetic heart disease. Biomarkers, molecules measurable in the blood, could inform the clinician by aiding in diagnosis, directing treatment, and predicting outcomes. We present an updated review of circulating biomarkers in hypertrophic cardiomyopathy...

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Detalles Bibliográficos
Autores principales: Matthia, Eldon L., Setteducato, Michael L., Elzeneini, Mohammed, Vernace, Nicholas, Salerno, Michael, Kramer, Christopher M., Keeley, Ellen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Contemporary Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851432/
https://www.ncbi.nlm.nih.gov/pubmed/36382968
http://dx.doi.org/10.1161/JAHA.122.027618
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author Matthia, Eldon L.
Setteducato, Michael L.
Elzeneini, Mohammed
Vernace, Nicholas
Salerno, Michael
Kramer, Christopher M.
Keeley, Ellen C.
author_facet Matthia, Eldon L.
Setteducato, Michael L.
Elzeneini, Mohammed
Vernace, Nicholas
Salerno, Michael
Kramer, Christopher M.
Keeley, Ellen C.
author_sort Matthia, Eldon L.
collection PubMed
description Hypertrophic cardiomyopathy is the most common genetic heart disease. Biomarkers, molecules measurable in the blood, could inform the clinician by aiding in diagnosis, directing treatment, and predicting outcomes. We present an updated review of circulating biomarkers in hypertrophic cardiomyopathy representing key pathologic processes including wall stretch, myocardial necrosis, fibrosis, inflammation, hypertrophy, and endothelial dysfunction, in addition to their clinical significance.
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spelling pubmed-98514322023-01-24 Circulating Biomarkers in Hypertrophic Cardiomyopathy Matthia, Eldon L. Setteducato, Michael L. Elzeneini, Mohammed Vernace, Nicholas Salerno, Michael Kramer, Christopher M. Keeley, Ellen C. J Am Heart Assoc Contemporary Review Hypertrophic cardiomyopathy is the most common genetic heart disease. Biomarkers, molecules measurable in the blood, could inform the clinician by aiding in diagnosis, directing treatment, and predicting outcomes. We present an updated review of circulating biomarkers in hypertrophic cardiomyopathy representing key pathologic processes including wall stretch, myocardial necrosis, fibrosis, inflammation, hypertrophy, and endothelial dysfunction, in addition to their clinical significance. John Wiley and Sons Inc. 2022-12-06 /pmc/articles/PMC9851432/ /pubmed/36382968 http://dx.doi.org/10.1161/JAHA.122.027618 Text en © 2022 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Contemporary Review
Matthia, Eldon L.
Setteducato, Michael L.
Elzeneini, Mohammed
Vernace, Nicholas
Salerno, Michael
Kramer, Christopher M.
Keeley, Ellen C.
Circulating Biomarkers in Hypertrophic Cardiomyopathy
title Circulating Biomarkers in Hypertrophic Cardiomyopathy
title_full Circulating Biomarkers in Hypertrophic Cardiomyopathy
title_fullStr Circulating Biomarkers in Hypertrophic Cardiomyopathy
title_full_unstemmed Circulating Biomarkers in Hypertrophic Cardiomyopathy
title_short Circulating Biomarkers in Hypertrophic Cardiomyopathy
title_sort circulating biomarkers in hypertrophic cardiomyopathy
topic Contemporary Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851432/
https://www.ncbi.nlm.nih.gov/pubmed/36382968
http://dx.doi.org/10.1161/JAHA.122.027618
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