Endothelial Extracellular Signal‐Regulated Kinase/Thromboxane A2/Prostanoid Receptor Pathway Aggravates Endothelial Dysfunction and Insulin Resistance in a Mouse Model of Metabolic Syndrome

BACKGROUND: Metabolic syndrome is characterized by insulin resistance, which impairs intracellular signaling pathways and endothelial NO bioactivity, leading to cardiovascular complications. Extracellular signal‐regulated kinase (ERK) is a major component of insulin signaling cascades that can be ac...

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Detalles Bibliográficos
Autores principales: Sato, Atsushi, Yumita, Yusuke, Kagami, Kazuki, Ishinoda, Yuki, Kimura, Toyokazu, Osaki, Ayumu, Toya, Takumi, Namba, Takayuki, Endo, Shogo, Ido, Yasuo, Nagatomo, Yuji, Satoh, Yasushi, Adachi, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851435/
https://www.ncbi.nlm.nih.gov/pubmed/36382966
http://dx.doi.org/10.1161/JAHA.122.027538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851435/
https://www.ncbi.nlm.nih.gov/pubmed/36382966
http://dx.doi.org/10.1161/JAHA.122.027538

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