Integrin α7 Mutations Are Associated With Adult‐Onset Cardiac Dysfunction in Humans and Mice

BACKGROUND: Integrin α7β1 is a major laminin receptor in skeletal and cardiac muscle. In skeletal muscle, integrin α7β1 plays an important role during muscle development and has been described as an important modifier of skeletal muscle diseases. The integrin α7β1 is also highly expressed in the hea...

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Detalles Bibliográficos
Autores principales: Bugiardini, Enrico, Nunes, Andreia M., Oliveira‐Santos, Ariany, Dagda, Marisela, Fontelonga, Tatiana M., Barraza‐Flores, Pamela, Pittman, Alan M., Morrow, Jasper M., Parton, Matthew, Houlden, Henry, Elliott, Perry M., Syrris, Petros, Maas, Roderick P., Akhtar, Mohammed M., Küsters, Benno, Raaphorst, Joost, Schouten, Meyke, Kamsteeg, Erik‐Jan, van Engelen, Baziel, Hanna, Michael G., Phadke, Rahul, Lopes, Luis R., Matthews, Emma, Burkin, Dean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851448/
https://www.ncbi.nlm.nih.gov/pubmed/36444867
http://dx.doi.org/10.1161/JAHA.122.026494

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