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Flow‐Induced Secretion of Endothelial Heparanase Regulates Cardiac Lipoprotein Lipase and Changes Following Diabetes

BACKGROUND: Lipoprotein lipase (LPL)‐derived fatty acid is a major source of energy for cardiac contraction. Synthesized in cardiomyocytes, LPL requires translocation to the vascular lumen for hydrolysis of lipoprotein triglyceride, an action mediated by endothelial cell (EC) release of heparanase....

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Detalles Bibliográficos
Autores principales:	Lee, Chae Syng, Zhai, Yajie, Shang, Rui, Wong, Trevor, Mattison, Aurora J., Cen, Haoning Howard, Johnson, James D., Vlodavsky, Israel, Hussein, Bahira, Rodrigues, Brian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851453/ https://www.ncbi.nlm.nih.gov/pubmed/36416172 http://dx.doi.org/10.1161/JAHA.122.027958

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