Ruxolitinib does not completely abrogate the functional capabilities of TLR4/9 ligand-activated NK cells

INTRODUCTION: Natural killer (NK) cells are lymphocytes from the innate immune system part of the first defense barrier against infected and transformed cells, representing 5%-15% of peripheral blood lymphocytes. The cytotoxic capacity of NK cells is controlled by a balance between inhibitory and ac...

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Detalles Bibliográficos
Autores principales: Mestre-Durán, Carmen, Martín-Cortázar, Carla, García-Solís, Blanca, Pernas, Alicia, Pertíñez, Lidia, Galán, Víctor, Sisinni, Luisa, Clares-Villa, Laura, Navarro-Zapata, Alfonso, Al-Akioui, Karima, Escudero, Adela, Ferreras, Cristina, Pérez-Martínez, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851469/
https://www.ncbi.nlm.nih.gov/pubmed/36685552
http://dx.doi.org/10.3389/fimmu.2022.1045316

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