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Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial
INTRODUCTION: Peripheral artery disease and cardiac disease are often comorbid conditions. Echocardiography is a diagnostic tool that can be performed preoperatively to risk stratify patients by a functional cardiac test. We hypothesized that ventricular dysfunction and valvular lesions were associa...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851553/ https://www.ncbi.nlm.nih.gov/pubmed/36656845 http://dx.doi.org/10.1371/journal.pone.0280531 |
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author | Meyer, Matthew J. Jameson, Slater A. Gillig, Edward J. Aggarwal, Ankur Ratcliffe, Sarah J. Baldwin, Mary Singh, Karen E. Clouse, W. Darrin Blank, Randal S. |
author_facet | Meyer, Matthew J. Jameson, Slater A. Gillig, Edward J. Aggarwal, Ankur Ratcliffe, Sarah J. Baldwin, Mary Singh, Karen E. Clouse, W. Darrin Blank, Randal S. |
author_sort | Meyer, Matthew J. |
collection | PubMed |
description | INTRODUCTION: Peripheral artery disease and cardiac disease are often comorbid conditions. Echocardiography is a diagnostic tool that can be performed preoperatively to risk stratify patients by a functional cardiac test. We hypothesized that ventricular dysfunction and valvular lesions were associated with an increased incidence of expanded major adverse cardiac events (Expanded MACE). METHODS AND MATERIALS: Retrospective cohort study from 2011 to 2020 including all patients from a major academic center who had vascular surgery and an echocardiographic study within two years of the index procedure. RESULTS: 813 patients were included in the study; a majority had a history of smoking (86%), an ASA score of 3 (65%), and were male (68%). Carotid endarterectomy was the most common surgery (24%) and the least common surgery was open abdominal aortic aneurysm repair (5%). We found no significant association between the echocardiographic findings of left ventricular dysfunction, right ventricular dysfunction, or valvular lesions and the postoperative development of Expanded MACE. CONCLUSIONS: The preoperative echocardiographic findings of left ventricular dysfunction, right ventricular dysfunction and moderate to severe valvular lesions were not predictive of an increased incidence of postoperative Expanded MACE. We identified a significant association between RV dysfunction and post-operative dialysis that should be interpreted carefully due to the small number of outcomes. The transition from open to endovascular surgery and advances in perioperative management may have led to improved cardiovascular outcomes. TRIAL REGISTRATION: Trial Registration: NCT04836702 (clinicaltrials.gov). https://www.google.com/search?client=firefox-b-d&q=NCT04836702. |
format | Online Article Text |
id | pubmed-9851553 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-98515532023-01-20 Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial Meyer, Matthew J. Jameson, Slater A. Gillig, Edward J. Aggarwal, Ankur Ratcliffe, Sarah J. Baldwin, Mary Singh, Karen E. Clouse, W. Darrin Blank, Randal S. PLoS One Research Article INTRODUCTION: Peripheral artery disease and cardiac disease are often comorbid conditions. Echocardiography is a diagnostic tool that can be performed preoperatively to risk stratify patients by a functional cardiac test. We hypothesized that ventricular dysfunction and valvular lesions were associated with an increased incidence of expanded major adverse cardiac events (Expanded MACE). METHODS AND MATERIALS: Retrospective cohort study from 2011 to 2020 including all patients from a major academic center who had vascular surgery and an echocardiographic study within two years of the index procedure. RESULTS: 813 patients were included in the study; a majority had a history of smoking (86%), an ASA score of 3 (65%), and were male (68%). Carotid endarterectomy was the most common surgery (24%) and the least common surgery was open abdominal aortic aneurysm repair (5%). We found no significant association between the echocardiographic findings of left ventricular dysfunction, right ventricular dysfunction, or valvular lesions and the postoperative development of Expanded MACE. CONCLUSIONS: The preoperative echocardiographic findings of left ventricular dysfunction, right ventricular dysfunction and moderate to severe valvular lesions were not predictive of an increased incidence of postoperative Expanded MACE. We identified a significant association between RV dysfunction and post-operative dialysis that should be interpreted carefully due to the small number of outcomes. The transition from open to endovascular surgery and advances in perioperative management may have led to improved cardiovascular outcomes. TRIAL REGISTRATION: Trial Registration: NCT04836702 (clinicaltrials.gov). https://www.google.com/search?client=firefox-b-d&q=NCT04836702. Public Library of Science 2023-01-19 /pmc/articles/PMC9851553/ /pubmed/36656845 http://dx.doi.org/10.1371/journal.pone.0280531 Text en © 2023 Meyer et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Meyer, Matthew J. Jameson, Slater A. Gillig, Edward J. Aggarwal, Ankur Ratcliffe, Sarah J. Baldwin, Mary Singh, Karen E. Clouse, W. Darrin Blank, Randal S. Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial |
title | Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial |
title_full | Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial |
title_fullStr | Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial |
title_full_unstemmed | Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial |
title_short | Clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: An observational trial |
title_sort | clinical implications of preoperative echocardiographic findings on cardiovascular outcomes following vascular surgery: an observational trial |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851553/ https://www.ncbi.nlm.nih.gov/pubmed/36656845 http://dx.doi.org/10.1371/journal.pone.0280531 |
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