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Obinutuzumab Effectively Depletes Key B-cell Subsets in Blood and Tissue in End-stage Renal Disease Patients

The THEORY study evaluated the effects of single and multiple doses of obinutuzumab, a type 2 anti-CD20 antibody that induces antibody-dependent cell-mediated cytotoxicity and direct cell death, in combination with standard of care in patients with end-stage renal disease. METHODS. We measured B-cel...

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Detalles Bibliográficos
Autores principales:	Looney, Cary M., Schroeder, Aaron, Tavares, Erica, Garg, Jay, Schindler, Thomas, Vincenti, Flavio, Redfield, Robert R., Jordan, Stanley C., Busque, Stephan, Woodle, E. Steve, Khan, Jared, Eastham, Jeffrey, Micallef, Sandrine, Austin, Cary D., Morimoto, Alyssa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Kidney Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851678/ https://www.ncbi.nlm.nih.gov/pubmed/36700064 http://dx.doi.org/10.1097/TXD.0000000000001436

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