P2X7R Mediates the Synergistic Effect of ATP and MSU Crystals to Induce Acute Gouty Arthritis

Activation of the nod-like receptor protein 3 (NLRP3) inflammasome by monosodium urate (MSU) crystals has been identified as the molecular basis for the acute inflammatory response in gouty arthritis. However, MSU crystals alone are not sufficient to induce acute gouty arthritis (AGA). Adenosine tri...

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Detalles Bibliográficos
Autores principales: Li, Xiaoling, Wan, An, Liu, Yiming, Li, Manyun, Zhu, Ziwen, Luo, Chengyu, Tao, Jinhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851801/
https://www.ncbi.nlm.nih.gov/pubmed/36686377
http://dx.doi.org/10.1155/2023/3317307

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