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3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism

Lyme neuroborreliosis (LNB), a tick-borne infection caused by spirochetes within the Borrelia burgdorferi sensu lato (s.L.) complex, is among the most prevalent bacterial central nervous system (CNS) infections in Europe and the US. Here we have screened a panel of low-passage B. burgdorferi s.l. is...

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Detalles Bibliográficos
Autores principales: Adams, Yvonne, Clausen, Anne Skovsbo, Jensen, Peter Østrup, Lager, Malin, Wilhelmsson, Peter, Henningson, Anna J., Lindgren, Per-Eric, Faurholt-Jepsen, Daniel, Mens, Helene, Kraiczy, Peter, Kragh, Kasper Nørskov, Bjarnsholt, Thomas, Kjaer, Andreas, Lebech, Anne-Mette, Jensen, Anja R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851883/
https://www.ncbi.nlm.nih.gov/pubmed/36686395
http://dx.doi.org/10.1016/j.isci.2022.105838

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