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Structure of a volume-regulated heteromeric LRRC8A/C channel

Volume-regulated anion channels (VRACs) participate in the cellular response to osmotic swelling. These membrane proteins consist of heteromeric assemblies of LRRC8 subunits, whose compositions determine permeation properties. Although structures of the obligatory LRRC8A, also referred to as SWELL1,...

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Detalles Bibliográficos
Autores principales: Rutz, Sonja, Deneka, Dawid, Dittmann, Antje, Sawicka, Marta, Dutzler, Raimund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851909/
https://www.ncbi.nlm.nih.gov/pubmed/36522427
http://dx.doi.org/10.1038/s41594-022-00899-0