Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis

The coordination mechanism of neural innate immune responses for axon regeneration is not well understood. Here, we showed that neuronal deletion of protein tyrosine phosphatase non-receptor type 2 sustains the IFNγ-STAT1 activity in retinal ganglion cells (RGCs) to promote axon regeneration after i...

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Detalles Bibliográficos
Autores principales: Wang, Xu, Yang, Chao, Wang, Xuejie, Miao, Jinmin, Chen, Weitao, Zhou, Yiren, Xu, Ying, An, Yongyan, Cheng, Aifang, Ye, Wenkang, Chen, Mengxian, Song, Dong, Yuan, Xue, Wang, Jiguang, Qian, Peiyuan, Ruohao Wu, Angela, Zhang, Zhong-Yin, Liu, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851977/
https://www.ncbi.nlm.nih.gov/pubmed/36370710
http://dx.doi.org/10.1016/j.neuron.2022.10.028

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