FtsH degrades kinetically stable dimers of cyclopropane fatty acid synthase via an internal degron

Targeted protein degradation plays important roles in stress responses in all cells. In E. coli, the membrane‐bound AAA+ FtsH protease degrades cytoplasmic and membrane proteins. Here, we demonstrate that FtsH degrades cyclopropane fatty acid (CFA) synthase, whose synthesis is induced upon nutrient...

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Detalles Bibliográficos
Autores principales: Hari, Sanjay B., Morehouse, Juhee P., Baker, Tania A., Sauer, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851988/
https://www.ncbi.nlm.nih.gov/pubmed/36456794
http://dx.doi.org/10.1111/mmi.15009

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