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Impaired Human Cardiac Cell Development due to NOTCH1 Deficiency

NOTCH1 pathogenic variants are implicated in multiple types of congenital heart defects including hypoplastic left heart syndrome, where the left ventricle is underdeveloped. It is unknown how NOTCH1 regulates human cardiac cell lineage determination and cardiomyocyte proliferation. In addition, mec...

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Detalles Bibliográficos
Autores principales:	Ye, Shiqiao, Wang, Cankun, Xu, Zhaohui, Lin, Hui, Wan, Xiaoping, Yu, Yang, Adhicary, Subhodip, Zhang, Joe Z., Zhou, Yang, Liu, Chun, Alonzo, Matthew, Bi, Jianli, Ramirez-Navarro, Angelina, Deschenes, Isabelle, Ma, Qin, Garg, Vidu, Wu, Joseph C., Zhao, Ming-Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852089/ https://www.ncbi.nlm.nih.gov/pubmed/36583388 http://dx.doi.org/10.1161/CIRCRESAHA.122.321398

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