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Current molecular biomarkers evaluation in gastric/gastroesophageal junction adenocarcinoma: pathologist does matter

The comprehensive molecular characterization of gastric and gastroesophageal junction adenocarcinomas has led to the improvement of targeted and more effective treatments. As a result, several biomarkers have been introduced into clinical practice and the implementation of innovative diagnostic tool...

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Detalles Bibliográficos
Autores principales: Businello, Gianluca, Angerilli, Valentina, Lonardi, Sara, Bergamo, Francesca, Valmasoni, Michele, Farinati, Fabio, Savarino, Edoardo, Spolverato, Gaya, Fassan, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852175/
https://www.ncbi.nlm.nih.gov/pubmed/35834132
http://dx.doi.org/10.1007/s13304-022-01330-5
Descripción
Sumario:The comprehensive molecular characterization of gastric and gastroesophageal junction adenocarcinomas has led to the improvement of targeted and more effective treatments. As a result, several biomarkers have been introduced into clinical practice and the implementation of innovative diagnostic tools is under study. Such assessments are mainly based on the evaluation of limited biopsy material in clinical practice. In this setting, the pathologist represents a key player in the selection of patients facilitating precision medicine approaches.