Urine cell-free DNA multi-omics to detect MRD and predict survival in bladder cancer patients

Circulating tumor DNA (ctDNA) sensitivity remains subpar for molecular residual disease (MRD) detection in bladder cancer patients. To remedy this problem, we focused on the biofluid most proximal to the disease, urine, and analyzed urine tumor DNA in 74 localized bladder cancer patients. We integra...

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Detalles Bibliográficos
Autores principales: Chauhan, Pradeep S., Shiang, Alexander, Alahi, Irfan, Sundby, R. Taylor, Feng, Wenjia, Gungoren, Bilge, Nawaf, Cayce, Chen, Kevin, Babbra, Ramandeep K., Harris, Peter K., Qaium, Faridi, Hatscher, Casey, Antiporda, Anna, Brunt, Lindsey, Mayer, Lindsey R., Shern, Jack F., Baumann, Brian C., Kim, Eric H., Reimers, Melissa A., Smith, Zachary L., Chaudhuri, Aadel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852243/
https://www.ncbi.nlm.nih.gov/pubmed/36658307
http://dx.doi.org/10.1038/s41698-022-00345-w

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