Interphase chromosomes of the Aedes aegypti mosquito are liquid crystalline and can sense mechanical cues

We use data-driven physical simulations to study the three-dimensional architecture of the Aedes aegypti genome. Hi-C maps exhibit both a broad diagonal and compartmentalization with telomeres and centromeres clustering together. Physical modeling reveals that these observations correspond to an ens...

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Detalles Bibliográficos
Autores principales: Contessoto, Vinícius G., Dudchenko, Olga, Aiden, Erez Lieberman, Wolynes, Peter G., Onuchic, José N., Di Pierro, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852290/
https://www.ncbi.nlm.nih.gov/pubmed/36658127
http://dx.doi.org/10.1038/s41467-023-35909-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852290/
https://www.ncbi.nlm.nih.gov/pubmed/36658127
http://dx.doi.org/10.1038/s41467-023-35909-2

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