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Interphase chromosomes of the Aedes aegypti mosquito are liquid crystalline and can sense mechanical cues
We use data-driven physical simulations to study the three-dimensional architecture of the Aedes aegypti genome. Hi-C maps exhibit both a broad diagonal and compartmentalization with telomeres and centromeres clustering together. Physical modeling reveals that these observations correspond to an ens...
Autores principales: | Contessoto, Vinícius G., Dudchenko, Olga, Aiden, Erez Lieberman, Wolynes, Peter G., Onuchic, José N., Di Pierro, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852290/ https://www.ncbi.nlm.nih.gov/pubmed/36658127 http://dx.doi.org/10.1038/s41467-023-35909-2 |
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