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Allyl isothiocyanate dry powder inhaler based on cyclodextrin-metal organic frameworks for pulmonary delivery

In this study, allyl isothiocyanate (AITC) was prepared as the dry powder inhalation by loading cyclodextrin metal-organic framework (CD-MOF) to enhance pulmonary delivery. β-CD-MOF and γ-CD-MOF both could be used to carry AITC with the optimal loading conditions (50˚C, n(CD): n(AITC) = 1:7, 7 h). C...

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Detalles Bibliográficos
Autores principales: Sun, Nianxia, Zhang, Min, Zhu, Wentao, Song, Pingping, Dai, Tingting, Huang, Peng, Han, Zhili, Wang, Dianlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852347/
https://www.ncbi.nlm.nih.gov/pubmed/36686390
http://dx.doi.org/10.1016/j.isci.2022.105910