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PHB2 promotes colorectal cancer cell proliferation and tumorigenesis through NDUFS1-mediated oxidative phosphorylation

The alteration of cellular energy metabolism is a hallmark of colorectal cancer (CRC). Accumulating evidence has suggested oxidative phosphorylation (OXPHOS) is upregulated to meet the demand for energy in tumor initiation and development. However, the role of OXPHOS and its regulatory mechanism in...

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Detalles Bibliográficos
Autores principales: Ren, Lin, Meng, Li, Gao, Jing, Lu, Mingdian, Guo, Chengyu, Li, Yunyun, Rong, Ziye, Ye, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852476/
https://www.ncbi.nlm.nih.gov/pubmed/36658121
http://dx.doi.org/10.1038/s41419-023-05575-9