A novel agonist with homobivalent single-domain antibodies that bind the FGF receptor 1 domain III functions as an FGF2 ligand

Fibroblast growth factor (FGF) is a multifunctional protein that exhibits a wide range of biological effects. Most commonly, it acts as a mitogen, but it also has regulatory, morphological, and endocrine effects. The four receptor subtypes of FGF are activated by more than 20 different FGF ligands....

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Detalles Bibliográficos
Autores principales: Yonehara, Ryo, Kumachi, Shigefumi, Kashiwagi, Kenji, Wakabayashi-Nakao, Kanako, Motohashi, Maiko, Murakami, Taihei, Yanagisawa, Teruhiko, Arai, Hidenao, Murakami, Akikazu, Ueno, Yukio, Nemoto, Naoto, Tsuchiya, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852558/
https://www.ncbi.nlm.nih.gov/pubmed/36529290
http://dx.doi.org/10.1016/j.jbc.2022.102804

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