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Cell-type specific synaptic plasticity in dorsal striatum is associated with punishment-resistance compulsive-like cocaine self-administration in mice
Addiction-related compulsion-like behavior can be modeled in rodents with drug self-administration (SA) despite harmful consequences. Recent studies suggest that the potentiation of glutamatergic transmission at the orbitofrontal cortex (OFC) to dorsal striatum (DS) synapses drives the transition fr...
Autores principales: | Pascoli, Vincent, Hiver, Agnès, Li, Yue, Harada, Masaya, Esmaeili, Vahid, Lüscher, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852591/ https://www.ncbi.nlm.nih.gov/pubmed/36071131 http://dx.doi.org/10.1038/s41386-022-01429-8 |
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