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Recurrent lung adenocarcinoma benefits from microwave ablation following multidisciplinary treatments: A case with long-term survival

Lung cancer has become the leading cause of cancer death all over the world. Nowadays, there is a consensus that the treatment of non-small cell lung cancer (NSCLC) prefers a combination of multidisciplinary comprehensive treatment and individualized treatment, which can significantly improve the pr...

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Autores principales: Jiang, Guanyu, Song, Chenghu, Xu, Yongrui, Wang, Shengfei, Li, Huixing, Lu, Rongguo, Wang, Xiaokun, Chen, Ruo, Mao, Wenjun, Zheng, Mingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852634/
https://www.ncbi.nlm.nih.gov/pubmed/36684300
http://dx.doi.org/10.3389/fsurg.2022.1038219
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author Jiang, Guanyu
Song, Chenghu
Xu, Yongrui
Wang, Shengfei
Li, Huixing
Lu, Rongguo
Wang, Xiaokun
Chen, Ruo
Mao, Wenjun
Zheng, Mingfeng
author_facet Jiang, Guanyu
Song, Chenghu
Xu, Yongrui
Wang, Shengfei
Li, Huixing
Lu, Rongguo
Wang, Xiaokun
Chen, Ruo
Mao, Wenjun
Zheng, Mingfeng
author_sort Jiang, Guanyu
collection PubMed
description Lung cancer has become the leading cause of cancer death all over the world. Nowadays, there is a consensus that the treatment of non-small cell lung cancer (NSCLC) prefers a combination of multidisciplinary comprehensive treatment and individualized treatment, which can significantly improve the prognosis of patients. Here, we report a female patient with recurrence-prone NSCLC. She had a decade-long disease course, during which the lesion recurred twice and finally cured with Multi-Disciplinary Treatment (MDT). An elderly female patient was admitted to the hospital after diagnosis of lung cancer, and treated with surgery and postoperative adjuvant chemotherapy. Five years later, suspicious lesions were found by computed tomography (CT) reexamination, and then confirmed tumor recurrence by puncture biopsy. Based on the genetic test results, gefitinib was used for subsequent targeted therapy, and the lesion gradually shrunk to disappear. However, the lesion appeared again two years later, after consultation the microwave ablation was adopted and the curative effect was excellent. At last, regular reexamination showed no abnormality, the patient has survived so far. The case proves the great benefit of multidisciplinary comprehensive treatment, especially microwave ablation for patient with recurrence-prone NSCLC. And the effect of systemic anti-tumor immune response induced by microwave ablation on lung cancer also needs to be further explored.
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spelling pubmed-98526342023-01-21 Recurrent lung adenocarcinoma benefits from microwave ablation following multidisciplinary treatments: A case with long-term survival Jiang, Guanyu Song, Chenghu Xu, Yongrui Wang, Shengfei Li, Huixing Lu, Rongguo Wang, Xiaokun Chen, Ruo Mao, Wenjun Zheng, Mingfeng Front Surg Surgery Lung cancer has become the leading cause of cancer death all over the world. Nowadays, there is a consensus that the treatment of non-small cell lung cancer (NSCLC) prefers a combination of multidisciplinary comprehensive treatment and individualized treatment, which can significantly improve the prognosis of patients. Here, we report a female patient with recurrence-prone NSCLC. She had a decade-long disease course, during which the lesion recurred twice and finally cured with Multi-Disciplinary Treatment (MDT). An elderly female patient was admitted to the hospital after diagnosis of lung cancer, and treated with surgery and postoperative adjuvant chemotherapy. Five years later, suspicious lesions were found by computed tomography (CT) reexamination, and then confirmed tumor recurrence by puncture biopsy. Based on the genetic test results, gefitinib was used for subsequent targeted therapy, and the lesion gradually shrunk to disappear. However, the lesion appeared again two years later, after consultation the microwave ablation was adopted and the curative effect was excellent. At last, regular reexamination showed no abnormality, the patient has survived so far. The case proves the great benefit of multidisciplinary comprehensive treatment, especially microwave ablation for patient with recurrence-prone NSCLC. And the effect of systemic anti-tumor immune response induced by microwave ablation on lung cancer also needs to be further explored. Frontiers Media S.A. 2023-01-06 /pmc/articles/PMC9852634/ /pubmed/36684300 http://dx.doi.org/10.3389/fsurg.2022.1038219 Text en © 2023 Jiang, Song, Xu, Wang, Li, Lu, Wang, Chen, Mao and Zheng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Jiang, Guanyu
Song, Chenghu
Xu, Yongrui
Wang, Shengfei
Li, Huixing
Lu, Rongguo
Wang, Xiaokun
Chen, Ruo
Mao, Wenjun
Zheng, Mingfeng
Recurrent lung adenocarcinoma benefits from microwave ablation following multidisciplinary treatments: A case with long-term survival
title Recurrent lung adenocarcinoma benefits from microwave ablation following multidisciplinary treatments: A case with long-term survival
title_full Recurrent lung adenocarcinoma benefits from microwave ablation following multidisciplinary treatments: A case with long-term survival
title_fullStr Recurrent lung adenocarcinoma benefits from microwave ablation following multidisciplinary treatments: A case with long-term survival
title_full_unstemmed Recurrent lung adenocarcinoma benefits from microwave ablation following multidisciplinary treatments: A case with long-term survival
title_short Recurrent lung adenocarcinoma benefits from microwave ablation following multidisciplinary treatments: A case with long-term survival
title_sort recurrent lung adenocarcinoma benefits from microwave ablation following multidisciplinary treatments: a case with long-term survival
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852634/
https://www.ncbi.nlm.nih.gov/pubmed/36684300
http://dx.doi.org/10.3389/fsurg.2022.1038219
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