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Neurodegeneration risk factor, EIF2AK3 (PERK), influences tau protein aggregation

Tauopathies are neurodegenerative diseases caused by pathologic misfolded tau protein aggregation in the nervous system. Population studies implicate EIF2AK3 (eukaryotic translation initiation factor 2 alpha kinase 3), better known as PERK (protein kinase R-like endoplasmic reticulum kinase), as a g...

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Detalles Bibliográficos
Autores principales:	Park, Goonho, Xu, Ke, Chea, Leon, Kim, Kyle, Safarta, Lance, Song, Keon-Hyoung, Wu, Jian, Park, Soyoung, Min, Hyejung, Hiramatsu, Nobuhiko, Han, Jaeseok, Lin, Jonathan H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852698/ https://www.ncbi.nlm.nih.gov/pubmed/36563857 http://dx.doi.org/10.1016/j.jbc.2022.102821

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