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Candidalysin: Connecting the pore forming mechanism of this virulence factor to its immunostimulatory properties

Candida albicans is a deadly pathogen responsible for millions of mucosal and systemic infections per year. The pathobiology of C. albicans is largely dependent on the damaging and immunostimulatory properties of the peptide candidalysin (CL), a key virulence factor. When CL forms pores in the plasm...

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Detalles Bibliográficos
Autores principales: Russell, Charles M., Rybak, Jennifer A., Miao, Jian, Peters, Brian M., Barrera, Francisco N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852700/
https://www.ncbi.nlm.nih.gov/pubmed/36581211
http://dx.doi.org/10.1016/j.jbc.2022.102829