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Candidalysin: Connecting the pore forming mechanism of this virulence factor to its immunostimulatory properties
Candida albicans is a deadly pathogen responsible for millions of mucosal and systemic infections per year. The pathobiology of C. albicans is largely dependent on the damaging and immunostimulatory properties of the peptide candidalysin (CL), a key virulence factor. When CL forms pores in the plasm...
Autores principales: | Russell, Charles M., Rybak, Jennifer A., Miao, Jian, Peters, Brian M., Barrera, Francisco N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852700/ https://www.ncbi.nlm.nih.gov/pubmed/36581211 http://dx.doi.org/10.1016/j.jbc.2022.102829 |
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