Cargando…
Smad2Δexon3 and Smad3 have distinct properties in signal transmission leading to TGF-β–induced cell motility
In mammalian cells, Smad2 and Smad3, two receptor-regulated Smad proteins, play crucial roles in the signal transmission of transforming growth factor-β (TGF-β) and are involved in various cell regulatory processes, including epithelial–mesenchymal transition–associated cell responses, that is, cell...
Autores principales: | Yokoyama, Takashi, Kuga, Takahito, Itoh, Yuka, Otake, Shigeo, Omata, Chiho, Saitoh, Masao, Miyazawa, Keiji |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852702/ https://www.ncbi.nlm.nih.gov/pubmed/36549646 http://dx.doi.org/10.1016/j.jbc.2022.102820 |
Ejemplares similares
-
TGF-β-induced cell motility requires downregulation of ARHGAPs to sustain Rac1 activity
por: Motizuki, Mitsuyoshi, et al.
Publicado: (2021) -
ZEB1 and oncogenic Ras constitute a regulatory switch for stimulus‐dependent E‐cadherin downregulation
por: Otake, Shigeo, et al.
Publicado: (2020) -
The expression of TGF-β1, Smad3, phospho-Smad3 and Smad7 is correlated with the development and invasion of nonfunctioning pituitary adenomas
por: Zhenye, Li, et al.
Publicado: (2014) -
TGF-β induces p53/Smads complex formation in the PAI-1 promoter to activate transcription
por: Kawarada, Yuki, et al.
Publicado: (2016) -
SMAD2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4
por: Bertrand-Chapel, Adrien, et al.
Publicado: (2022)