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Successful pancreatoduodenectomy of de novo duodenal malignancy after orthotopic liver transplantation: A case report
INTRODUCTION: Liver transplantation is a risk factor for premalignant and malignant changes of the duodenum. De novo duodenal malignancy is seldom reported after liver transplantation. CASE REPORT: The present study reports a case of an asymptomatic 67-year-old male patient who underwent liver trans...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852733/ https://www.ncbi.nlm.nih.gov/pubmed/36684304 http://dx.doi.org/10.3389/fsurg.2022.1068215 |
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author | Ji, Linhua Xu, Danhua Zhu, Chunchao Xu, Jia Cao, Hui Zhao, Gang |
author_facet | Ji, Linhua Xu, Danhua Zhu, Chunchao Xu, Jia Cao, Hui Zhao, Gang |
author_sort | Ji, Linhua |
collection | PubMed |
description | INTRODUCTION: Liver transplantation is a risk factor for premalignant and malignant changes of the duodenum. De novo duodenal malignancy is seldom reported after liver transplantation. CASE REPORT: The present study reports a case of an asymptomatic 67-year-old male patient who underwent liver transplantation more than 10 years ago and subsequently developed duodenal malignancy. Endoscopic biopsy of the de novo duodenal malignancy indicated duodenal carcinoma and pancreatoduodenectomy (PD) was performed. The patient was successfully discharged 12 days after the surgery. A metastatic lesion occurred at the right seventh rib 14 months after the pancreatoduodenectomy. Postoperative pathological examination indicated hepatocellular carcinoma metastasis. CONCLUSIONS: To the best of our knowledge, this case type has not been previously reported. The present study sheds light on the development, the treatment, the prognosis, and the management of a new type of de novo duodenal malignancy. |
format | Online Article Text |
id | pubmed-9852733 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98527332023-01-21 Successful pancreatoduodenectomy of de novo duodenal malignancy after orthotopic liver transplantation: A case report Ji, Linhua Xu, Danhua Zhu, Chunchao Xu, Jia Cao, Hui Zhao, Gang Front Surg Surgery INTRODUCTION: Liver transplantation is a risk factor for premalignant and malignant changes of the duodenum. De novo duodenal malignancy is seldom reported after liver transplantation. CASE REPORT: The present study reports a case of an asymptomatic 67-year-old male patient who underwent liver transplantation more than 10 years ago and subsequently developed duodenal malignancy. Endoscopic biopsy of the de novo duodenal malignancy indicated duodenal carcinoma and pancreatoduodenectomy (PD) was performed. The patient was successfully discharged 12 days after the surgery. A metastatic lesion occurred at the right seventh rib 14 months after the pancreatoduodenectomy. Postoperative pathological examination indicated hepatocellular carcinoma metastasis. CONCLUSIONS: To the best of our knowledge, this case type has not been previously reported. The present study sheds light on the development, the treatment, the prognosis, and the management of a new type of de novo duodenal malignancy. Frontiers Media S.A. 2023-01-06 /pmc/articles/PMC9852733/ /pubmed/36684304 http://dx.doi.org/10.3389/fsurg.2022.1068215 Text en © 2023 Ji, Xu, Zhu, Xu, Cao and Zhao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Surgery Ji, Linhua Xu, Danhua Zhu, Chunchao Xu, Jia Cao, Hui Zhao, Gang Successful pancreatoduodenectomy of de novo duodenal malignancy after orthotopic liver transplantation: A case report |
title | Successful pancreatoduodenectomy of de novo duodenal malignancy after orthotopic liver transplantation: A case report |
title_full | Successful pancreatoduodenectomy of de novo duodenal malignancy after orthotopic liver transplantation: A case report |
title_fullStr | Successful pancreatoduodenectomy of de novo duodenal malignancy after orthotopic liver transplantation: A case report |
title_full_unstemmed | Successful pancreatoduodenectomy of de novo duodenal malignancy after orthotopic liver transplantation: A case report |
title_short | Successful pancreatoduodenectomy of de novo duodenal malignancy after orthotopic liver transplantation: A case report |
title_sort | successful pancreatoduodenectomy of de novo duodenal malignancy after orthotopic liver transplantation: a case report |
topic | Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852733/ https://www.ncbi.nlm.nih.gov/pubmed/36684304 http://dx.doi.org/10.3389/fsurg.2022.1068215 |
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