Ligand and structure-based approaches for the exploration of structure–activity relationships of fusidic acid derivatives as antibacterial agents

Introduction: Fusidic acid (FA) has been widely applied in the clinical prevention and treatment of bacterial infections. Nonetheless, its clinical application has been limited due to its narrow antimicrobial spectrum and some side effects. Purpose: Therefore, it is necessary to explore the structur...

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Detalles Bibliográficos
Autores principales: Zheng, Wende, Tu, Borong, Zhang, Zhen, Li, Jinxuan, Yan, Zhenping, Su, Kaize, Deng, Duanyu, Sun, Ying, Wang, Xu, Zhang, Bingjie, Zhang, Kun, Wong, Wing-Leung, Wu, Panpan, Hong, Weiqian David, Ang, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852990/
https://www.ncbi.nlm.nih.gov/pubmed/36688047
http://dx.doi.org/10.3389/fchem.2022.1094841

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