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Histone deacetylase inhibitors mitigate antipsychotic risperidone-induced motor side effects in aged mice and in a mouse model of Alzheimer’s disease

Antipsychotic drugs are still widely prescribed to control various severe neuropsychiatric symptoms in the elderly and dementia patients although they are off-label use in the United States. However, clinical practice shows greater side effects and lower efficacy of antipsychotics for this vulnerabl...

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Detalles Bibliográficos
Autores principales: Rodriguez, Guadalupe, Fisher, Daniel W., McClarty, Bryan, Montalvo-Ortiz, Janitza, Cui, Qiaoling, Chan, C. Savio, Dong, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852991/
https://www.ncbi.nlm.nih.gov/pubmed/36684015
http://dx.doi.org/10.3389/fpsyt.2022.1020831