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Structural basis for ubiquitylation by HOIL-1

The linear ubiquitin chain assembly complex synthesises linear Ub chains which constitute a binding and activation platform for components of the TNF signalling pathway. One of the components of LUBAC is the ubiquitin ligase HOIL-1 which has been shown to generate oxyester linkages on several protei...

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Detalles Bibliográficos
Autores principales:	Wu, Qilong, Koliopoulos, Marios G., Rittinger, Katrin, Stieglitz, Benjamin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853177/ https://www.ncbi.nlm.nih.gov/pubmed/36685275 http://dx.doi.org/10.3389/fmolb.2022.1098144

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