Grape seed proanthocyanidin extract targets p66Shc to regulate mitochondrial biogenesis and dynamics in diabetic kidney disease

Mitochondrial biogenesis and dynamics are associated with renal mitochondrial dysfunction and the pathophysiological development of diabetic kidney disease (DKD). Decreased p66Shc expression prevents DKD progression by significantly regulating mitochondrial function. Grape seed proanthocyanidin extr...

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Detalles Bibliográficos
Autores principales: Song, Yiyun, Yu, Hui, Sun, Qiaoling, Pei, Fei, Xia, Qing, Gao, Zhaoli, Li, Xianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853208/
https://www.ncbi.nlm.nih.gov/pubmed/36686673
http://dx.doi.org/10.3389/fphar.2022.1035755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853208/
https://www.ncbi.nlm.nih.gov/pubmed/36686673
http://dx.doi.org/10.3389/fphar.2022.1035755

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