Recombinant Simian Varicella Virus-Simian Immunodeficiency Virus Vaccine Induces T and B Cell Functions and Provides Partial Protection against Repeated Mucosal SIV Challenges in Rhesus Macaques

HIV vaccine mediated efficacy, using an expanded live attenuated recombinant varicella virus-vectored SIV rSVV-SIVgag/env vaccine prime with adjuvanted SIV-Env and SIV-Gag protein boosts, was evaluated in a female rhesus macaques (RM) model against repeated intravaginal SIV challenges. Vaccination i...

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Detalles Bibliográficos
Autores principales: Pahar, Bapi, Gray, Wayne, Fahlberg, Marissa, Grasperge, Brooke, Hunter, Meredith, Das, Arpita, Mabee, Christopher, Aye, Pyone Pyone, Schiro, Faith, Hensley, Krystle, Ratnayake, Aneeka, Goff, Kelly, LaBranche, Celia, Shen, Xiaoying, Tomaras, Georgia D., DeMarco, C. Todd, Montefiori, David, Kissinger, Patricia, Marx, Preston A., Traina-Dorge, Vicki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853323/
https://www.ncbi.nlm.nih.gov/pubmed/36560823
http://dx.doi.org/10.3390/v14122819

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