Uncovering the Most Kinetically Influential Reaction Pathway Driving the Generation of HCN from Oxyma/DIC Adduct: A Theoretical Study

[Image: see text] The combination of ethyl (hydroxyimino)cyanoacetate (Oxyma) and diisopropylcarbodiimide (DIC) has demonstrated superior performance in amino acid activation for peptide synthesis. However, it was recently reported that Oxyma and DIC could react to generate undesired hydrogen cyanid...

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Detalles Bibliográficos
Autores principales: Gui, Lingfeng, Adjiman, Claire S., Galindo, Amparo, Sayyed, Fareed Bhasha, Kolis, Stanley P., Armstrong, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853495/
https://www.ncbi.nlm.nih.gov/pubmed/36692415
http://dx.doi.org/10.1021/acs.iecr.2c03145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853495/
https://www.ncbi.nlm.nih.gov/pubmed/36692415
http://dx.doi.org/10.1021/acs.iecr.2c03145

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