Cargando…
Uncovering the Most Kinetically Influential Reaction Pathway Driving the Generation of HCN from Oxyma/DIC Adduct: A Theoretical Study
[Image: see text] The combination of ethyl (hydroxyimino)cyanoacetate (Oxyma) and diisopropylcarbodiimide (DIC) has demonstrated superior performance in amino acid activation for peptide synthesis. However, it was recently reported that Oxyma and DIC could react to generate undesired hydrogen cyanid...
Autores principales: | Gui, Lingfeng, Adjiman, Claire S., Galindo, Amparo, Sayyed, Fareed Bhasha, Kolis, Stanley P., Armstrong, Alan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853495/ https://www.ncbi.nlm.nih.gov/pubmed/36692415 http://dx.doi.org/10.1021/acs.iecr.2c03145 |
Ejemplares similares
-
Understanding OxymaPure as a Peptide Coupling Additive:
A Guide to New Oxyma Derivatives
por: Manne, Srinivasa Rao, et al.
Publicado: (2022) -
OxymaPure/DIC: An Efficient Reagent for the Synthesis of a Novel Series of 4-[2-(2-Acetylaminophenyl)-2-oxo-acetylamino] Benzoyl Amino Acid Ester Derivatives
por: El-Faham, Ayman, et al.
Publicado: (2013) -
Carbodiimide-Mediated Beckmann Rearrangement of Oxyma-B as a Side Reaction in Peptide Synthesis
por: Orlandin, Andrea, et al.
Publicado: (2022) -
TOMBU and COMBU as Novel Uronium-Type Peptide Coupling Reagents Derived from Oxyma-B
por: Jad, Yahya E., et al.
Publicado: (2014) -
Who Are the Most Influential Emergency Physicians on Twitter?
por: Riddell, Jeff, et al.
Publicado: (2017)