Evaluation of an Adoptive Cellular Therapy-Based Vaccine in a Transgenic Mouse Model of α-synucleinopathy

[Image: see text] Aggregated α-synuclein, a major constituent of Lewy bodies plays a crucial role in the pathogenesis of α-synucleinopathies (SPs) such as Parkinson’s disease (PD). PD is affected by the innate and adaptive arms of the immune system, and recently both active and passive immunotherapi...

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Autores principales: Chu, Winston T., Hall, Jesse, Gurrala, Anjela, Becsey, Alexander, Raman, Shreya, Okun, Michael S., Flores, Catherine T., Giasson, Benoit I., Vaillancourt, David E., Vedam-Mai, Vinata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853504/
https://www.ncbi.nlm.nih.gov/pubmed/36571847
http://dx.doi.org/10.1021/acschemneuro.2c00539

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