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Case report: ‘Photodynamics of Subependymal Giant Cell Astrocytoma with 5-Aminolevulinic acid’
Subependymal Giant Cell Astrocytoma (SEGA) is a common diagnosis in patients with Tuberous Sclerosis. Although surgical treatment is often required, resection may entail a significant risk for cognitive function given the anatomical relation with critical structures such as the fornices and subgenua...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853524/ https://www.ncbi.nlm.nih.gov/pubmed/36684213 http://dx.doi.org/10.3389/fsurg.2022.1065979 |
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author | Ghani, Imran Patel, Sabina Ghimire, Prajwal Bodi, Istvan Bhangoo, Ranjeev Vergani, Francesco Ashkan, Keyoumars Lavrador, Jose Pedro |
author_facet | Ghani, Imran Patel, Sabina Ghimire, Prajwal Bodi, Istvan Bhangoo, Ranjeev Vergani, Francesco Ashkan, Keyoumars Lavrador, Jose Pedro |
author_sort | Ghani, Imran |
collection | PubMed |
description | Subependymal Giant Cell Astrocytoma (SEGA) is a common diagnosis in patients with Tuberous Sclerosis. Although surgical treatment is often required, resection may entail a significant risk for cognitive function given the anatomical relation with critical structures such as the fornices and subgenual area. Therefore, target subtotal resections using minimal invasive approaches focused in the higher metabolic areas are valuable options to preserve quality of life while addressing specific problems caused by the tumor, such as hydrocephalus or progressive growth of a specific component of the tumor. In this report, the authors explore the potential role of 5-ALA in the identification of highly metabolic areas during SEGA resection in the context of minimal invasive approaches. |
format | Online Article Text |
id | pubmed-9853524 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98535242023-01-21 Case report: ‘Photodynamics of Subependymal Giant Cell Astrocytoma with 5-Aminolevulinic acid’ Ghani, Imran Patel, Sabina Ghimire, Prajwal Bodi, Istvan Bhangoo, Ranjeev Vergani, Francesco Ashkan, Keyoumars Lavrador, Jose Pedro Front Surg Surgery Subependymal Giant Cell Astrocytoma (SEGA) is a common diagnosis in patients with Tuberous Sclerosis. Although surgical treatment is often required, resection may entail a significant risk for cognitive function given the anatomical relation with critical structures such as the fornices and subgenual area. Therefore, target subtotal resections using minimal invasive approaches focused in the higher metabolic areas are valuable options to preserve quality of life while addressing specific problems caused by the tumor, such as hydrocephalus or progressive growth of a specific component of the tumor. In this report, the authors explore the potential role of 5-ALA in the identification of highly metabolic areas during SEGA resection in the context of minimal invasive approaches. Frontiers Media S.A. 2023-01-06 /pmc/articles/PMC9853524/ /pubmed/36684213 http://dx.doi.org/10.3389/fsurg.2022.1065979 Text en © 2023 Ghani, Patel, Ghimire, Bodi, Bhangoo, Vergani, Ashkan and Lavrador. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Surgery Ghani, Imran Patel, Sabina Ghimire, Prajwal Bodi, Istvan Bhangoo, Ranjeev Vergani, Francesco Ashkan, Keyoumars Lavrador, Jose Pedro Case report: ‘Photodynamics of Subependymal Giant Cell Astrocytoma with 5-Aminolevulinic acid’ |
title | Case report: ‘Photodynamics of Subependymal Giant Cell Astrocytoma with 5-Aminolevulinic acid’ |
title_full | Case report: ‘Photodynamics of Subependymal Giant Cell Astrocytoma with 5-Aminolevulinic acid’ |
title_fullStr | Case report: ‘Photodynamics of Subependymal Giant Cell Astrocytoma with 5-Aminolevulinic acid’ |
title_full_unstemmed | Case report: ‘Photodynamics of Subependymal Giant Cell Astrocytoma with 5-Aminolevulinic acid’ |
title_short | Case report: ‘Photodynamics of Subependymal Giant Cell Astrocytoma with 5-Aminolevulinic acid’ |
title_sort | case report: ‘photodynamics of subependymal giant cell astrocytoma with 5-aminolevulinic acid’ |
topic | Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853524/ https://www.ncbi.nlm.nih.gov/pubmed/36684213 http://dx.doi.org/10.3389/fsurg.2022.1065979 |
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