Cargando…

Ruthenium(II) Polypyridyl Complexes as FRET Donors: Structure- and Sequence-Selective DNA-Binding and Anticancer Properties

[Image: see text] Ruthenium(II) polypyridyl complexes (RPCs) that emit from metal-to-ligand charge transfer (MLCT) states have been developed as DNA probes and are being examined as potential anticancer agents. Here, we report that MLCT-emissive RPCs that bind DNA undergo Förster resonance energy tr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Elgar, Christopher E., Yusoh, Nur Aininie, Tiley, Paul R., Kolozsvári, Natália, Bennett, Laura G., Gamble, Amelia, Péan, Emmanuel V., Davies, Matthew L., Staples, Christopher J., Ahmad, Haslina, Gill, Martin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853847/ https://www.ncbi.nlm.nih.gov/pubmed/36607895 http://dx.doi.org/10.1021/jacs.2c11111

Ejemplares similares

Combining PARP Inhibition with Platinum, Ruthenium or Gold Complexes for Cancer Therapy
por: Yusoh, Nur Aininie, et al.
Publicado: (2020)

Synergy of ruthenium metallo-intercalator, [Ru(dppz)(2)(PIP)](2+), with PARP inhibitor Olaparib in non-small cell lung cancer cells
por: Yusoh, Nur Aininie, et al.
Publicado: (2023)

Discovery of Ruthenium(II) Metallocompound and Olaparib Synergy for Cancer Combination Therapy
por: Yusoh, Nur Aininie, et al.
Publicado: (2023)

Synthesis and Optimization of Mesoporous Silica Nanoparticles for Ruthenium Polypyridyl Drug Delivery
por: Harun, Siti Norain, et al.
Publicado: (2021)

A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition
por: Gill, Martin R., et al.
Publicado: (2016)

Corrigendum: A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition
por: Gill, Martin R., et al.
Publicado: (2016)

Targeting the endoplasmic reticulum with a membrane-interactive luminescent ruthenium(ii) polypyridyl complex
por: Gill, Martin R., et al.
Publicado: (2013)

A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis
por: Gill, Martin R., et al.
Publicado: (2022)

Effects of chirality on the intracellular localization of binuclear ruthenium(II) polypyridyl complexes
por: Svensson, Frida R., et al.
Publicado: (2012)

Correction: Chiral ruthenium polypyridyl complexes as mitochondria-targeted apoptosis inducers
por: Chen, Tianfeng, et al.
Publicado: (2018)

Recent Advances on Octahedral Polypyridyl Ruthenium(II) Complexes as Antimicrobial Agents
por: Yang, Yulin, et al.
Publicado: (2018)

Octahedral ruthenium (II) polypyridyl complexes as antimicrobial agents against mycobacterium
por: Liao, Guojian, et al.
Publicado: (2017)

Stabilization of Long-Looped i-Motif DNA by Polypyridyl Ruthenium Complexes
por: Pages, Benjamin J., et al.
Publicado: (2019)

A Mechanism Study of Redox Reactions of the Ruthenium-oxo-polypyridyl Complex
por: Chen, Bao-Long, et al.
Publicado: (2023)

Evaluation of the In Vitro and In Vivo Efficacy of Ruthenium Polypyridyl Compounds against Breast Cancer
por: Lenis-Rojas, Oscar A., et al.
Publicado: (2021)

Designing photolabile ruthenium polypyridyl crosslinkers for hydrogel formation and multiplexed, visible-light degradation
por: Rapp, Teresa L., et al.
Publicado: (2019)

Ultrafast transient IR spectroscopy and DFT calculations of ruthenium(ii) polypyridyl complexes
por: Sun, Qinchao, et al.
Publicado: (2017)

New ruthenium polypyridyl complexes as potential sensors of acetonitrile and catalysts for water oxidation
por: Abate, Pedro O., et al.
Publicado: (2022)

Ruthenium Polypyridyl Complex Bound to a Unimolecular Chair-Form G-Quadruplex
por: McQuaid, Kane T., et al.
Publicado: (2022)

Disruption of microtubule function in cultured human cells by a cytotoxic ruthenium(ii) polypyridyl complex
por: Alatrash, Nagham, et al.
Publicado: (2019)

Influence of the Steric Bulk and Solvent on the Photoreactivity of Ruthenium Polypyridyl Complexes Coordinated to l-Proline
por: Cuello-Garibo, Jordi-Amat, et al.
Publicado: (2017)

Ruthenium(II) Polypyridyl Complexes and Their Use as Probes and Photoreactive Agents for G-quadruplexes Labelling
por: Jiang, Julie, et al.
Publicado: (2022)

Steric hindrance, ligand ejection and associated photocytotoxic properties of ruthenium(II) polypyridyl complexes
por: Herrera-Ramírez, Piedad, et al.
Publicado: (2023)

Ligand Rigidity Steers the Selectivity and Efficiency of the Photosubstitution Reaction of Strained Ruthenium Polypyridyl Complexes
por: Hakkennes, Matthijs L. A., et al.
Publicado: (2023)

Reactivity of non-organometallic ruthenium(II) polypyridyl complexes and their application as catalysts for hydride transfer reactions
por: Chrzanowska, Marta, et al.
Publicado: (2023)

Data on the characterization and anticancer action of iron(II) polypyridyl complexes
por: Chen, Jingjing, et al.
Publicado: (2016)

Ruthenium(ii)-polypyridyl zirconium(iv) metal–organic frameworks as a new class of sensitized solar cells
por: Maza, W. A., et al.
Publicado: (2016)

Ruthenium polypyridyl complexes and their modes of interaction with DNA: Is there a correlation between these interactions and the antitumor activity of the compounds?
por: Corral, Eva, et al.
Publicado: (2008)

Alkyne Functionalization of a Photoactivated Ruthenium Polypyridyl Complex for Click-Enabled Serum Albumin Interaction Studies
por: Busemann, Anja, et al.
Publicado: (2020)

Diastereoselective Synthesis and Two-Step Photocleavage of Ruthenium Polypyridyl Complexes Bearing a Bis(thioether) Ligand
por: Meijer, Michael S., et al.
Publicado: (2019)

Ruthenium(II) Polypyridyl Complexes for Antimicrobial Photodynamic Therapy: Prospects for Application in Cystic Fibrosis Lung Airways
por: Youf, Raphaëlle, et al.
Publicado: (2022)

Good Vibrations Report on the DNA Quadruplex Binding of an Excited State Amplified Ruthenium Polypyridyl IR Probe
por: Stitch, Mark, et al.
Publicado: (2023)

Chiral Ruthenium(II) Polypyridyl Complexes: Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity and Cellular Uptake
por: Yu, Qianqian, et al.
Publicado: (2012)

Luminescent ruthenium(II) polypyridyl complexes acted as radiosensitizer for pancreatic cancer by enhancing radiation-induced DNA damage
por: Zhou, Yuyang, et al.
Publicado: (2019)

Self‐Assembly of Copper Polypyridyl Supramolecular Metallopolymers to Achieve Enhanced Anticancer Efficacy
por: Lai, Lanhai, et al.
Publicado: (2019)

Chemical Swarming: Depending on Concentration, an Amphiphilic Ruthenium Polypyridyl Complex Induces Cell Death via Two Different Mechanisms
por: Siewert, Bianka, et al.
Publicado: (2016)

Stabilization of Ruthenium(II) Polypyridyl Chromophores on Mesoporous TiO(2) Electrodes: Surface Reductive Electropolymerization and Silane Chemistry
por: Wu, Lei, et al.
Publicado: (2019)

Synthesis of O-1–O-6 Substituted Positional Isomers of d-Glucose–Thioether Ligands and Their Ruthenium Polypyridyl Conjugates
por: Lameijer, Lucien N., et al.
Publicado: (2018)

Cellular and cell-free studies of catalytic DNA cleavage by ruthenium polypyridyl complexes containing redox-active intercalating ligands
por: Griffith, Cynthia, et al.
Publicado: (2017)

Ruthenium Polypyridyl Complex Inhibits Growth and Metastasis of Breast Cancer Cells by Suppressing FAK signaling with Enhancement of TRAIL-induced Apoptosis
por: Cao, Wenqiang, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_6mhtt11qhak4qjd3afkqv268uo