Efficient Synthesis of DNA Duplexes Containing Reduced Acetaldehyde Interstrand Cross-Links

[Image: see text] DNA interstrand cross-links (ICLs) prevent DNA replication and transcription and can lead to potentially lethal events, such as cancer or bone marrow failure. ICLs are typically repaired by proteins within the Fanconi Anemia (FA) pathway, although the details of the pathway are not...

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Detalles Bibliográficos
Autores principales: Morton, Sally B., Finger, L. David, van der Sluijs, Roxanne, Mulcrone, William D., Hodskinson, Michael, Millington, Christopher L., Vanhinsbergh, Christina, Patel, Ketan J., Dickman, Mark J., Knipscheer, Puck, Grasby, Jane A., Williams, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853853/
https://www.ncbi.nlm.nih.gov/pubmed/36584283
http://dx.doi.org/10.1021/jacs.2c10070

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