Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA

[Image: see text] Phenotypic screening is a powerful approach to identify novel antibiotics, but elucidation of the targets responsible for the antimicrobial activity is often challenging in the case of compounds with a polypharmacological mode of action. Here, we show that activity-based protein pr...

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Detalles Bibliográficos
Autores principales: Bakker, Alexander T., Kotsogianni, Ioli, Mirenda, Liza, Straub, Verena M., Avalos, Mariana, van den Berg, Richard J. B. H. N., Florea, Bogdan I., van Wezel, Gilles P., Janssen, Antonius P. A., Martin, Nathaniel I., van der Stelt, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853856/
https://www.ncbi.nlm.nih.gov/pubmed/36584241
http://dx.doi.org/10.1021/jacs.2c10819

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