Enhancement of the haemostatic effect of platelets in the presence of high normal concentrations of von Willebrand factor for critically ill patients needing platelet transfusion—a protocol for the will-plate randomised controlled trial

INTRODUCTION: von Willebrand Factor (vWF) is a key protein mediating platelet adhesion on the surface of damaged endothelia. To the best of our knowledge, no trial exists that investigated the effect of platelet transfusion in combination with the administration of balanced vWF in severe blood loss,...

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Detalles Bibliográficos
Autores principales: Herrmann, Goetz, Blum, Andrea, Bolliger, Daniel, Achermann, Rita, Estermann, Anna, Gebhard, Caroline Eva, Henn, Anne, Huber, Jan, Singh, Jasprit, Todorov, Atanas, Zehnder, Tatjana, Zellweger, Núria, Buser, Andreas, Tsakiris, Dimitrios A., Hollinger, Alexa, Siegemund, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854010/
https://www.ncbi.nlm.nih.gov/pubmed/36670471
http://dx.doi.org/10.1186/s13063-022-06876-8

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