Cargando…

Monte Carlo dosimetry of the (60)Co sources of a new GZP3 HDR afterloading system

BACKGROUND: The purpose of this work was to obtain the dosimetric parameters of the new GZP3 (60)Co high-dose-rate afterloading system launched by the Nuclear Power Institute of China, which is comprised of two different (60)Co sources. METHODS: The Monte Carlo software Geant4 and EGSnrc were employ...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Junxiang, Kang, Shengwei, Wang, Pei, Li, Jie, Wang, Xianliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854037/
https://www.ncbi.nlm.nih.gov/pubmed/36670476
http://dx.doi.org/10.1186/s13014-023-02207-6
_version_ 1784873030789365760
author Wu, Junxiang
Kang, Shengwei
Wang, Pei
Li, Jie
Wang, Xianliang
author_facet Wu, Junxiang
Kang, Shengwei
Wang, Pei
Li, Jie
Wang, Xianliang
author_sort Wu, Junxiang
collection PubMed
description BACKGROUND: The purpose of this work was to obtain the dosimetric parameters of the new GZP3 (60)Co high-dose-rate afterloading system launched by the Nuclear Power Institute of China, which is comprised of two different (60)Co sources. METHODS: The Monte Carlo software Geant4 and EGSnrc were employed to derive accurate calculations of the dosimetric parameters of the new GZP3 (60)Co brachytherapy source in the range of 0–10 cm, following the formalism proposed by American Association of Physicists in Medicine reports TG43 and TG43U1. Results of the two Monte Carlo codes were compared to verify the accuracy of the data. The source was located in the center of a 30-cm-radius theoretical sphere water phantom. RESULTS: For channels 1 and 2 of the new GZP3 (60)Co afterloading system, the results of the dose-rate constant (Λ) were 1.115 cGy h(−1) U(−1) and 1.112 cGy h(−1) U(−1), and for channel 3 they were 1.116 cGy h(−1) U(−1) and 1.113 cGy h(−1) U(−1) according to the Geant4 and EGSnrc, respectively. The radial dose function in the range of 0.25–10.0 cm in a longitudinal direction was calculated, and the fitting formulas for the function were obtained. The polynomial function for the radial dose function and the anisotropy function (1D and 2D) with a [Formula: see text] of 0°–175° and an r of 0.5–10.0 cm were obtained. The curves of the radial function and the anisotropy function fitted well compared with the two Monte Carlo software. CONCLUSION: These dosimetric data sets can be used as input data for TPS calculations and quality control for the new GZP3 (60)Co afterloading system.
format Online
Article
Text
id pubmed-9854037
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-98540372023-01-21 Monte Carlo dosimetry of the (60)Co sources of a new GZP3 HDR afterloading system Wu, Junxiang Kang, Shengwei Wang, Pei Li, Jie Wang, Xianliang Radiat Oncol Research BACKGROUND: The purpose of this work was to obtain the dosimetric parameters of the new GZP3 (60)Co high-dose-rate afterloading system launched by the Nuclear Power Institute of China, which is comprised of two different (60)Co sources. METHODS: The Monte Carlo software Geant4 and EGSnrc were employed to derive accurate calculations of the dosimetric parameters of the new GZP3 (60)Co brachytherapy source in the range of 0–10 cm, following the formalism proposed by American Association of Physicists in Medicine reports TG43 and TG43U1. Results of the two Monte Carlo codes were compared to verify the accuracy of the data. The source was located in the center of a 30-cm-radius theoretical sphere water phantom. RESULTS: For channels 1 and 2 of the new GZP3 (60)Co afterloading system, the results of the dose-rate constant (Λ) were 1.115 cGy h(−1) U(−1) and 1.112 cGy h(−1) U(−1), and for channel 3 they were 1.116 cGy h(−1) U(−1) and 1.113 cGy h(−1) U(−1) according to the Geant4 and EGSnrc, respectively. The radial dose function in the range of 0.25–10.0 cm in a longitudinal direction was calculated, and the fitting formulas for the function were obtained. The polynomial function for the radial dose function and the anisotropy function (1D and 2D) with a [Formula: see text] of 0°–175° and an r of 0.5–10.0 cm were obtained. The curves of the radial function and the anisotropy function fitted well compared with the two Monte Carlo software. CONCLUSION: These dosimetric data sets can be used as input data for TPS calculations and quality control for the new GZP3 (60)Co afterloading system. BioMed Central 2023-01-20 /pmc/articles/PMC9854037/ /pubmed/36670476 http://dx.doi.org/10.1186/s13014-023-02207-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Wu, Junxiang
Kang, Shengwei
Wang, Pei
Li, Jie
Wang, Xianliang
Monte Carlo dosimetry of the (60)Co sources of a new GZP3 HDR afterloading system
title Monte Carlo dosimetry of the (60)Co sources of a new GZP3 HDR afterloading system
title_full Monte Carlo dosimetry of the (60)Co sources of a new GZP3 HDR afterloading system
title_fullStr Monte Carlo dosimetry of the (60)Co sources of a new GZP3 HDR afterloading system
title_full_unstemmed Monte Carlo dosimetry of the (60)Co sources of a new GZP3 HDR afterloading system
title_short Monte Carlo dosimetry of the (60)Co sources of a new GZP3 HDR afterloading system
title_sort monte carlo dosimetry of the (60)co sources of a new gzp3 hdr afterloading system
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854037/
https://www.ncbi.nlm.nih.gov/pubmed/36670476
http://dx.doi.org/10.1186/s13014-023-02207-6
work_keys_str_mv AT wujunxiang montecarlodosimetryofthe60cosourcesofanewgzp3hdrafterloadingsystem
AT kangshengwei montecarlodosimetryofthe60cosourcesofanewgzp3hdrafterloadingsystem
AT wangpei montecarlodosimetryofthe60cosourcesofanewgzp3hdrafterloadingsystem
AT lijie montecarlodosimetryofthe60cosourcesofanewgzp3hdrafterloadingsystem
AT wangxianliang montecarlodosimetryofthe60cosourcesofanewgzp3hdrafterloadingsystem