Verapamil-loaded supramolecular hydrogel patch attenuates metabolic dysfunction-associated fatty liver disease via restoration of autophagic clearance of aggregated proteins and inhibition of NLRP3

BACKGROUND: Obesity, a serious threat to public health, is linked to chronic metabolic complications including insulin resistance, type-2 diabetes, and metabolic dysfunction-associated fatty liver disease (MAFLD). Current obesity medications are challenged by poor effectiveness, poor patient complia...

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Detalles Bibliográficos
Autores principales: Kim, Do Kyung, Han, Daewon, Bae, Jeongyun, Kim, Haeil, Lee, Solji, Kim, Jong-Seok, Jeong, Young-Gil, Shin, Jongdae, Park, Hwan-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854054/
https://www.ncbi.nlm.nih.gov/pubmed/36670488
http://dx.doi.org/10.1186/s40824-023-00342-5

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