Formyl peptide receptor 2 activation by mitochondrial formyl peptides stimulates the neutrophil proinflammatory response via the ERK pathway and exacerbates ischemia–reperfusion injury

BACKGROUND: Ischemia–reperfusion injury (IRI) is an inevitable process in renal transplantation that significantly increases the risk of delayed graft function, acute rejection, and even graft loss. Formyl peptide receptor 2 (FPR2) is an important receptor in multiple septic and aseptic injuries, bu...

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Detalles Bibliográficos
Autores principales: Cao, Yirui, Chen, Juntao, Liu, Feng, Qi, Guisheng, Zhao, Yufeng, Xu, Shihao, Wang, Jiyan, Zhu, Tongyu, Zhang, Yi, Jia, Yichen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854225/
https://www.ncbi.nlm.nih.gov/pubmed/36658472
http://dx.doi.org/10.1186/s11658-023-00416-1

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