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Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging
MOTS-c is a peptide encoded by the short open reading frame of the mitochondrial 12S rRNA gene. It is significantly expressed in response to stress or exercise and translocated to the nucleus, where it regulates the expression of stress adaptation-related genes with antioxidant response elements (AR...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854231/ https://www.ncbi.nlm.nih.gov/pubmed/36670507 http://dx.doi.org/10.1186/s12967-023-03885-2 |