Glioma-derived CCL2 and CCL7 mediate migration of immune suppressive CCR2(+)/CX3CR1(+) M-MDSCs into the tumor microenvironment in a redundant manner

Glioblastoma (GBM) is the most common and malignant primary brain tumor, resulting in poor survival despite aggressive therapies. GBM is characterized in part by a highly heterogeneous and immunosuppressive tumor microenvironment (TME) made up predominantly of infiltrating peripheral immune cells. O...

Descripción completa

Detalles Bibliográficos
Autores principales: Takacs, Gregory P., Kreiger, Christian J., Luo, Defang, Tian, Guimei, Garcia, Julia S., Deleyrolle, Loic P., Mitchell, Duane A., Harrison, Jeffrey K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854274/
https://www.ncbi.nlm.nih.gov/pubmed/36685592
http://dx.doi.org/10.3389/fimmu.2022.993444

Ejemplares similares

Ejemplares similares