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Phosphatidyl Inositol 3-Kinase (PI3K)-Inhibitor CDZ173 protects against LPS-induced osteolysis

A major complication of a joint replacement is prosthesis loosening caused by inflammatory osteolysis, leading to the revision of the operation. This is due to the abnormal activation of osteoclast differentiation and function caused by periprosthetic infection. Therefore, targeting abnormally activ...

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Detalles Bibliográficos
Autores principales:	Wu, Zuoxing, Li, Xuedong, Chen, Xiaohui, He, Xuemei, Chen, Yu, Zhang, Long, Li, Zan, Yang, Mengyu, Yuan, Guixin, Shi, Baohong, Chen, Ning, Li, Na, Feng, Haotian, Zhou, Mengyu, Rui, Gang, Xu, Feng, Xu, Ren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854393/ https://www.ncbi.nlm.nih.gov/pubmed/36686650 http://dx.doi.org/10.3389/fphar.2022.1021714

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