CRISPR/Cas9-editing of KISS1 to generate pigs with hypogonadotropic hypogonadism as a castration free trait

Introduction: Most male pigs are surgically castrated to avoid puberty-derived boar taint and aggressiveness. However, this surgical intervention represents a welfare concern in swine production. Disrupting porcine KISS1 is hypothesized to delay or abolish puberty by inducing variable hypogonadotrop...

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Detalles Bibliográficos
Autores principales: Flórez, Julio M., Martins, Kyra, Solin, Staci, Bostrom, Jonathan R., Rodríguez-Villamil, Paula, Ongaratto, Felipe, Larson, Sabreena A., Ganbaatar, Uyanga, Coutts, Alexander W., Kern, Doug, Murphy, Thomas W., Kim, Eui-Soo, Carlson, Daniel F., Huisman, Abe, Sonstegard, Tad S., Lents, Clay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854396/
https://www.ncbi.nlm.nih.gov/pubmed/36685939
http://dx.doi.org/10.3389/fgene.2022.1078991

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