Cargando…

Identification of Lipocalin 2 as a Ferroptosis-Related Key Gene Associated with Hypoxic-Ischemic Brain Damage via STAT3/NF-κB Signaling Pathway

Hypoxic-ischemic brain damage (HIBD) is a common cause of death or mental retardation in newborns. Ferroptosis is a novel form of iron-dependent cell death driven by lipid peroxidation, and recent studies have confirmed that ferroptosis plays an important role in the development of HIBD. However, HI...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Lianxiang, Deng, Liyan, Chen, Yongtong, Ding, Rui, Li, Xiaoling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854551/ https://www.ncbi.nlm.nih.gov/pubmed/36671050 http://dx.doi.org/10.3390/antiox12010186

Ejemplares similares

Asiaticoside attenuates neonatal hypoxic–ischemic brain damage through inhibiting TLR4/NF-κB/STAT3 pathway
por: Zhou, Yu, et al.
Publicado: (2020)

New Insights into Mechanisms of Ferroptosis Associated with Immune Infiltration in Neonatal Hypoxic-Ischemic Brain Damage
por: Li, Shangbin, et al.
Publicado: (2022)

Molecular mechanisms of ferroptosis and relevance to inflammation
por: Deng, Liyan, et al.
Publicado: (2022)

Lipocalin 2 potentially contributes to tumorigenesis from colitis via IL-6/STAT3/NF-κB signaling pathway
por: Kim, Se Lim, et al.
Publicado: (2022)

Ferroptosis: A Promising Therapeutic Target for Neonatal Hypoxic-Ischemic Brain Injury
por: Peeples, Eric S., et al.
Publicado: (2022)

Prophylactic inhibition of NF-κB expression in microglia leads to attenuation of hypoxic ischemic injury of the immature brain
por: Zaghloul, Nahla, et al.
Publicado: (2020)

Myricetin attenuates hypoxic-ischemic brain damage in neonatal rats via NRF2 signaling pathway
por: Chen, Tingting, et al.
Publicado: (2023)

Peptidome analysis of cerebrospinal fluid in neonates with hypoxic-ischemic brain damage
por: Hou, Xuewen, et al.
Publicado: (2020)

Lipocalin2 as a plasma marker for tumors with hypoxic regions
por: Nakamura, Ibuki, et al.
Publicado: (2014)

NF-κB signaling pathway inhibition suppresses hippocampal neuronal apoptosis and cognitive impairment via RCAN1 in neonatal rats with hypoxic-ischemic brain damage
por: Fang, Hua, et al.
Publicado: (2019)

Genistein mitigates oxidative stress and inflammation by regulating Nrf2/HO-1 and NF-κB signaling pathways in hypoxic-ischemic brain damage in neonatal mice
por: Li, Yuan, et al.
Publicado: (2022)

Tanshinone IIA improves hypoxic ischemic encephalopathy through TLR-4-mediated NF-κB signal pathway
por: Fang, Chengzhi, et al.
Publicado: (2018)

Glycyrrhizin Attenuates Hypoxic-Ischemic Brain Damage by Inhibiting Ferroptosis and Neuroinflammation in Neonatal Rats via the HMGB1/GPX4 Pathway
por: Zhu, Kaiyi, et al.
Publicado: (2022)

Measurement of thalamus and cortical damages in hypoxic ischemic encephalopathy
por: Sohn, GyeongMo, et al.
Publicado: (2023)

Research advances in the role of endogenous neurogenesis on neonatal hypoxic-ischemic brain damage
por: Chen, Andi, et al.
Publicado: (2022)

Mesenchymal stem cells suppress neuronal apoptosis and decrease IL-10 release via the TLR2/NFκB pathway in rats with hypoxic-ischemic brain damage
por: Gu, Yan, et al.
Publicado: (2015)

Hepatic NF‐κB‐Inducing Kinase and Inhibitor of NF‐κB Kinase Subunit α Promote Liver Oxidative Stress, Ferroptosis, and Liver Injury
por: Zhong, Xiao, et al.
Publicado: (2021)

Temporal regulation of HIF-1 and NF-κB in hypoxic hepatocarcinoma cells
por: Jiang, Yuan, et al.
Publicado: (2015)

NF-κB mediated regulation of tumor cell proliferation in hypoxic microenvironment
por: Rastogi, Shubham, et al.
Publicado: (2023)

ER stress drives Lipocalin 2 upregulation in prostate cancer cells in an NF-κB-dependent manner
por: Mahadevan, Navin R, et al.
Publicado: (2011)

The Lipocalin2 Gene is Regulated in Mammary Epithelial Cells by NFκB and C/EBP In Response to Mycoplasma
por: Zhao, Wei, et al.
Publicado: (2020)

Xue-Jie-San restricts ferroptosis in Crohn’s disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop
por: Gao, Ying, et al.
Publicado: (2023)

Iron-Bound Lipocalin-2 Protects Renal Cell Carcinoma from Ferroptosis
por: Meier, Julia K., et al.
Publicado: (2021)

Clinical Implications of Epigenetic Dysregulation in Perinatal Hypoxic-Ischemic Brain Damage
por: Bustelo, Martín, et al.
Publicado: (2020)

Resatorvid protects against hypoxic-ischemic brain damage in neonatal rats
por: Jiang, Li-Jun, et al.
Publicado: (2020)

Immunomodulatory Mechanism and Potential Therapies for Perinatal Hypoxic-Ischemic Brain Damage
por: Min, Ying-Jun, et al.
Publicado: (2020)

Neuroprotective Mechanism of Icariin on Hypoxic Ischemic Brain Damage in Neonatal Mice
por: Wang, Mengxia, et al.
Publicado: (2022)

Neutrophil Gelatinase-associated Lipocalin Significantly Correlates with Ischemic Damage in Patients Undergoing Laparoscopic Partial Nephrectomy
por: Savran Karadeniz, Meltem, et al.
Publicado: (2019)

Targeting ferroptosis-based cancer therapy using nanomaterials: strategies and applications
por: Luo, Lianxiang, et al.
Publicado: (2021)

STAT3/NF-κB decoy oligodeoxynucleotides inhibit atherosclerosis through regulation of the STAT/NF-κB signaling pathway in a mouse model of atherosclerosis
por: An, Hyun-Jin, et al.
Publicado: (2023)

Ferroptosis-related gene AKR1C1 predicts the prognosis of non-small cell lung cancer
por: Huang, Fangfang, et al.
Publicado: (2021)

Long Non-coding RNA H19 Deteriorates Hypoxic-Ischemic Brain Damage by Interacting with MicroRNA-140-5p and STAT3
por: Lu, Qian, et al.
Publicado: (2022)

Regulatory Networks Involving STATs, IRFs, and NFκB in Inflammation
por: Platanitis, Ekaterini, et al.
Publicado: (2018)

LOX-1 mediates inflammatory activation of microglial cells through the p38-MAPK/NF-κB pathways under hypoxic-ischemic conditions
por: Aoki, Yoshinori, et al.
Publicado: (2023)

Neuroprotection of lamotrigine on hypoxic-ischemic brain damage in neonatal rats: Relations to administration time and doses
por: Yi, Yong-Hong, et al.
Publicado: (2008)

Lipocalin 2 induces visual impairment by promoting ferroptosis in retinal ischemia-reperfusion injury
por: Mei, Tingfang, et al.
Publicado: (2023)

The mechanism of colon tissue damage mediated by HIF-1α/NF-κB/STAT1 in high-altitude environment
por: Cheng, Junfei, et al.
Publicado: (2022)

Delayed onset hypokinetic-rigid syndrome due to hypoxic-ischemic damage of the striatum
por: Moudrous, Walid, et al.
Publicado: (2016)

Early predictors of brain damage in full-term newborns with hypoxic ischemic encephalopathy
por: Alkholy, Usama M, et al.
Publicado: (2017)

Comparison of the Effects of Citicoline and Piracetam on Hypoxic-ischemic Brain Damage in Neonatal Rabbits
por: EBRAHIMI, Sedigheh, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a245ri5cqokj4srfo8jugepa5v