New Characterization of Multi-Drug Resistance of Streptococcus suis and Biofilm Formation from Swine in Heilongjiang Province of China

The aim of this study was to investigate the antimicrobial resistance profiles and genotypes of Streptococcus suis in Heilongjiang Province, China. A total of 29 S. suis were isolated from 332 samples collected from 6 pig farms. The results showed that serotypes 2, 4 and 9 were prevalent, and all th...

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Autores principales: Dong, Chun-Liu, Che, Rui-Xiang, Wu, Tong, Qu, Qian-Wei, Chen, Mo, Zheng, Si-Di, Cai, Xue-Hui, Wang, Gang, Li, Yan-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854593/
https://www.ncbi.nlm.nih.gov/pubmed/36671333
http://dx.doi.org/10.3390/antibiotics12010132
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author Dong, Chun-Liu
Che, Rui-Xiang
Wu, Tong
Qu, Qian-Wei
Chen, Mo
Zheng, Si-Di
Cai, Xue-Hui
Wang, Gang
Li, Yan-Hua
author_facet Dong, Chun-Liu
Che, Rui-Xiang
Wu, Tong
Qu, Qian-Wei
Chen, Mo
Zheng, Si-Di
Cai, Xue-Hui
Wang, Gang
Li, Yan-Hua
author_sort Dong, Chun-Liu
collection PubMed
description The aim of this study was to investigate the antimicrobial resistance profiles and genotypes of Streptococcus suis in Heilongjiang Province, China. A total of 29 S. suis were isolated from 332 samples collected from 6 pig farms. The results showed that serotypes 2, 4 and 9 were prevalent, and all the clinical isolates were resistant to at least two antibacterial drugs. The most resisted drugs were macrolides, and the least resisted drugs were fluoroquinolones. Resistant genes ermB and aph (3′)-IIIa were highly distributed among the isolates, with the detection rates of 79.31% and 75.86%. The formation of biofilm could be observed in all the isolated S. suis, among which D-1, LL-1 and LL-3 strains formed stronger biofilm structure than other strains. The results indicate that S. suis in Heilongjiang Province presents a multi-drug resistance to commonly used antimicrobial drugs, which was caused by the same target gene, the dissemination of drug resistance genes, and bacterial biofilm.
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spelling pubmed-98545932023-01-21 New Characterization of Multi-Drug Resistance of Streptococcus suis and Biofilm Formation from Swine in Heilongjiang Province of China Dong, Chun-Liu Che, Rui-Xiang Wu, Tong Qu, Qian-Wei Chen, Mo Zheng, Si-Di Cai, Xue-Hui Wang, Gang Li, Yan-Hua Antibiotics (Basel) Article The aim of this study was to investigate the antimicrobial resistance profiles and genotypes of Streptococcus suis in Heilongjiang Province, China. A total of 29 S. suis were isolated from 332 samples collected from 6 pig farms. The results showed that serotypes 2, 4 and 9 were prevalent, and all the clinical isolates were resistant to at least two antibacterial drugs. The most resisted drugs were macrolides, and the least resisted drugs were fluoroquinolones. Resistant genes ermB and aph (3′)-IIIa were highly distributed among the isolates, with the detection rates of 79.31% and 75.86%. The formation of biofilm could be observed in all the isolated S. suis, among which D-1, LL-1 and LL-3 strains formed stronger biofilm structure than other strains. The results indicate that S. suis in Heilongjiang Province presents a multi-drug resistance to commonly used antimicrobial drugs, which was caused by the same target gene, the dissemination of drug resistance genes, and bacterial biofilm. MDPI 2023-01-10 /pmc/articles/PMC9854593/ /pubmed/36671333 http://dx.doi.org/10.3390/antibiotics12010132 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dong, Chun-Liu
Che, Rui-Xiang
Wu, Tong
Qu, Qian-Wei
Chen, Mo
Zheng, Si-Di
Cai, Xue-Hui
Wang, Gang
Li, Yan-Hua
New Characterization of Multi-Drug Resistance of Streptococcus suis and Biofilm Formation from Swine in Heilongjiang Province of China
title New Characterization of Multi-Drug Resistance of Streptococcus suis and Biofilm Formation from Swine in Heilongjiang Province of China
title_full New Characterization of Multi-Drug Resistance of Streptococcus suis and Biofilm Formation from Swine in Heilongjiang Province of China
title_fullStr New Characterization of Multi-Drug Resistance of Streptococcus suis and Biofilm Formation from Swine in Heilongjiang Province of China
title_full_unstemmed New Characterization of Multi-Drug Resistance of Streptococcus suis and Biofilm Formation from Swine in Heilongjiang Province of China
title_short New Characterization of Multi-Drug Resistance of Streptococcus suis and Biofilm Formation from Swine in Heilongjiang Province of China
title_sort new characterization of multi-drug resistance of streptococcus suis and biofilm formation from swine in heilongjiang province of china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854593/
https://www.ncbi.nlm.nih.gov/pubmed/36671333
http://dx.doi.org/10.3390/antibiotics12010132
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